- Case Report
- Reninoma: a rare cause of curable hypertension
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Ji Hye Kim, Ji Hyun Kim, Myung Hyun Cho, Eujin Park, Hye Sun Hyun, Yo Han Ahn, Hee Gyung Kang, Kyung Chul Moon, Il-Soo Ha, Hae Il Cheong
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Clin Exp Pediatr. 2019;62(4):144-147. Published online October 29, 2018
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The most common type of refractory hypertension found in children is secondary hypertension, which is a potentially curable disease. Reninoma, a renin-secreting juxtaglomerular cell tumor, is a rare cause of severe hypertension that is usually diagnosed in adolescents and young adults. Surgical resection of the tumor completely cures the hypertension of patients with reninoma. The typical clinical presentation of reninoma... |
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- Original Article
- Oncology
- Posttransplantation lymphoproliferative disorder after pediatric solid organ transplantation: experiences of 20 years in a single center
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Hyung Joo Jeong, Yo Han Ahn, Eujin Park, Youngrok Choi, Nam-Joon Yi, Jae Sung Ko, Sang Il Min, Jong Won Ha, Il-Soo Ha, Hae Il Cheong, Hee Gyung Kang
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Clin Exp Pediatr. 2017;60(3):86-93. Published online March 27, 2017
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Purpose To evaluate the clinical spectrum of posttransplantation lymphoproliferative disorder (PTLD) after solid organ transplantation (SOT) in children. MethodsWe retrospectively reviewed the medical records of 18 patients with PTLD who underwent liver (LT) or kidney transplantation (KT) between January 1995 and December 2014 in Seoul National University Children's Hospital. ResultsEighteen patients (3.9% of pediatric SOTs; LT:KT, 11:7; male to female, 9:9) were diagnosed... |
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- Case Report
- Genetics and Metabolism
- A nonsense PAX6 mutation in a family with congenital aniridia
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Kyoung Hee Han, Hye Jin Lee, Il-Soo Ha, Hee Gyung Kang, Hae Il Cheong
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Clin Exp Pediatr. 2016;59(Suppl 1):S1-S4. Published online November 30, 2016
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Congenital aniridia is a rare ocular malformation that presents with severe hypoplasia of the iris and various ocular manifestations. Most cases of congenital aniridia are known to be related to mutations in the paired box gene-6 (PAX6), which is an essential gene in eye development. Herein, we report a familial case of autosomal dominant congenital aniridia with four affected members... |
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- Nephrology (Genitourinary)
- A novel mutation of CLCNKB in a Korean patient of mixed phenotype of Bartter-Gitelman syndrome
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Hee-Won Cho, Sang Taek Lee, Heeyeon Cho, Hae Il Cheong
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Clin Exp Pediatr. 2016;59(Suppl 1):S103-S106. Published online November 30, 2016
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Bartter syndrome (BS) is an inherited renal tubular disorder characterized by low or normal blood pressure, hypokalemic metabolic alkalosis, and hyperreninemic hyperaldosteronism. Type III BS is caused by loss-of-function mutations in CLCNKB encoding basolateral ClC-Kb. The clinical phenotype of patients with CLCNKB mutations has been known to be highly variable, and cases that are difficult to categorize as type III... |
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- Immunology
- A familial case of Blau syndrome caused by a novel NOD2 genetic mutation
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Woojoong Kim, Eujin Park, Yo Han Ahn, Jiwon M. Lee, Hee Gyung Kang, Byung Joo Kim, Il-Soo Ha, Hae Il Cheong
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Clin Exp Pediatr. 2016;59(Suppl 1):S5-S9. Published online November 30, 2016
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Blau syndrome (BS) is a rare autosomal dominant, inflammatory syndrome that is characterized by the clinical triad of granulomatous dermatitis, symmetric arthritis, and recurrent uveitis. Mutations in the nucleotide oligomerization domain 2 (NOD2) gene are responsible for causing BS. To date, up to 30 Blau-associated genetic mutations have been identified within this gene. We report a novel NOD2 genetic mutation... |
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- Nephrology (Genitourinary)
- Bilateral iliac and popliteal arterial thrombosis in a child with focal segmental glomerulosclerosis
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Kyoung Hee Han, Ji Youn Park, Seung-Kee Min, Il-Soo Ha, Hae Il Cheong, Hee Gyung Kang
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Clin Exp Pediatr. 2016;59(5):242-245. Published online May 31, 2016
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Thromboembolic complications (TECs) are clinically important sequelae of nephrotic syndrome (NS). The incidence of TECs in children is approximately 2%–5%. The veins are the most commonly affected sites, particularly the deep veins in the legs, the inferior vena cava, the superior vena cava, and the renal veins. Arterial thrombosis, which is less common, typically occurs in the cerebral, pulmonary, and... |
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- Review Article
- Nephrotic syndrome: what's new, what's hot?
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Hee Gyung Kang, Hae Il Cheong
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Clin Exp Pediatr. 2015;58(8):275-282. Published online August 21, 2015
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While the incidence of nephrotic syndrome (NS) is decreasing in Korea, the morbidity of difficult-to-treat NS is significant. Efforts to minimize treatment toxicity showed that prolonged treatment after an initial treatment for 2-3 months with glucocorticosteroids was not effective in reducing frequent relapses. For steroid-dependent NS, rituximab, a monoclonal antibody against the CD20 antigen on B cells, was proven to... |
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- Case Report
- Autosomal dominant hypocalcemia with Bartter syndrome due to a novel activating mutation of calcium sensing receptor, Y829C
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Keun Hee Choi, Choong Ho Shin, Sei Won Yang, Hae Il Cheong
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Clin Exp Pediatr. 2015;58(4):148-153. Published online April 22, 2015
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The calcium sensing receptor (CaSR) plays an important role in calcium homeostasis. Activating mutations of CaSR cause autosomal dominant hypocalcemia by affecting parathyroid hormone secretion in parathyroid gland and calcium resorption in kidney. They can also cause a type 5 Bartter syndrome by inhibiting the apical potassium channel in the thick ascending limb of the loop of Henle in the... |
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- Original Article
- Outcomes of chronic dialysis in Korean children with respect to survival rates and causes of death
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Hye Jin Chang, Kyoung Hee Han, Min Hyun Cho, Young Seo Park, Hee Gyung Kang, Hae Il Cheong, Il Soo Ha
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Clin Exp Pediatr. 2014;57(3):135-139. Published online March 31, 2014
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Purpose Adult Korean patients on chronic dialysis have a 9-year survival rate of 50%, with cardiovascular problems being the most significant cause of death. The 2011 annual report of the North American Pediatric Renal Trials and Collaborative Studies group reported 3-year survival rates of 93.4% and relatively poorer survival in younger patients. MethodsIn this study, we have reviewed data from Korean Pediatric... |
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- Case Report
- Shiga toxin-associated hemolytic uremic syndrome complicated by intestinal perforation in a child with typical hemolytic uremic syndrome
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Hye Jin Chang, Hwa Young Kim, Jae Hong Choi, Hyun Jin Choi, Jae Sung Ko, Il Soo Ha, Hae Il Cheong, Yong Choi, Hee Gyung Kang
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Clin Exp Pediatr. 2014;57(2):96-99. Published online February 24, 2014
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Hemolytic uremic syndrome (HUS) is one of the most common causes of acute renal failure in childhood and is primarily diagnosed in up to 4.5% of children who undergo chronic renal replacement therapy. Escherichia coli serotype O157:H7 is the predominant bacterial strain identified in patients with HUS; more than 100 types of Shiga toxin-producing enterohemorrhagic E. coli (EHEC) subtypes have... |
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- Original Article
- Intravenous fluid prescription practices among pediatric residents in Korea
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Jiwon M. Lee, Younghwa Jung, Se Eun Lee, Jun Ho Lee, Kee Hyuck Kim, Ja Wook Koo, Young Seo Park, Hae Il Cheong, Il-Soo Ha, Yong Choi, Hee Gyung Kang
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Clin Exp Pediatr. 2013;56(7):282-285. Published online July 19, 2013
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Purpose Recent studies have established the association between hypotonic fluids administration and hospital-acquired hyponatremia in children. The present paper investigated the pattern of current practice in intravenous fluid prescription among Korean pediatric residents, to underscore the need for updated education. MethodsA survey-based analysis was carried out. Pediatric residents at six university hospitals in Korea completed a survey consisting of four questions. Each... |
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- Case Report
- A case of hemolytic uremic syndrome preceded by intussusception
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Eun Young Ko, Joo Young Kim, Hye Jin Lee, Hyun Seung Lee, Ji Whan Han, Young Hoon Kim, Jin Tack Kim, Hae Il Cheong, Pil Sang Jang
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Clin Exp Pediatr. 2011;54(4):176-178. Published online April 30, 2011
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Hemolytic-uremic syndrome (HUS) is the most common cause of acute renal failure in young children. It is classically characterized by the triad of microangiopathic hemolytic anemia, thrombocytopenia, and uremia. Further, not only is intussusception one of the differential diagnoses of HUS but it may also become a complication during disease progression. We report a case of HUS preceded by intussusception... |
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- A case of pseudohypoaldosteronism type 1 with a mutation in the mineralocorticoid receptor gene
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Se Eun Lee, Yun Hye Jung, Kyoung Hee Han, Hyun Kyung Lee, Hee Gyung Kang, Il Soo Ha, Yong Choi, Hae Il Cheong
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Clin Exp Pediatr. 2011;54(2):90-93. Published online February 28, 2011
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Pseudohypoaldosteronism type 1 (PHA1) is a rare form of mineralocorticoid resistance characterized in newborns by salt wasting with dehydration, hyperkalemia and failure to thrive. This disease is heterogeneous in etiology and includes autosomal dominant PHA1 owing to mutations of the NR3C2 gene encoding the mineralocorticoid receptor, autosomal recessive PHA1 due to mutations of the epithelial sodium channel (ENaC) gene, and... |
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- Hypokalemic periodic paralysis; two different genes responsible for similar clinical manifestations
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Hunmin Kim, Hee Hwang, Hae Il Cheong, Hye Won Park
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Clin Exp Pediatr. 2011;54(11):473-476. Published online November 30, 2011
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Primary hypokalemic periodic paralysis (HOKPP) is an autosomal dominant disorder manifesting as recurrent periodic flaccid paralysis and concomitant hypokalemia. HOKPP is divided into type 1 and type 2 based on the causative gene. Although 2 different ion channels have been identified as the molecular genetic cause of HOKPP, the clinical manifestations between the 2 groups are similar. We report the... |
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- Renal transplantation in a patient with Bartter syndrome and glomerulosclerosis
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Se Eun Lee, Kyoung Hee Han, Yun Hye Jung, Hyun Kyung Lee, Hee Gyung Kang, Kyung Chul Moon, Il Soo Ha, Yong Choi, Hae Il Cheong
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Clin Exp Pediatr. 2011;54(1):36-39. Published online January 31, 2011
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Bartter syndrome (BS) is a clinically and genetically heterogeneous inherited renal tube disorder characterized by renal salt wasting, hypokalemic metabolic alkalosis and normotensive hyperreninemic hyperaldosteronism. There have been several case reports of BS complicated by focal segmental glomerulosclerosis (FSGS). Here, we have reported the case of a BS patient who developed FSGS and subsequent end-stage renal disease (ESRD) and provided... |
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- A case of Bartter syndrome type I with atypical presentations
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Eun Hye Lee, Ju Sun Heo, Hyun Kyung Lee, Kyung Hee Han, Hee Gyung Kang, Il Soo Ha, Yong Choi, Hae Il Cheong
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Clin Exp Pediatr. 2010;53(8):809-813. Published online August 31, 2010
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Bartter syndrome (BS) is an autosomal recessively inherited rare renal tubular disorder characterized by hypokalemic metabolic alkalosis and hyperreninemic hyperaldosteronism with normal to low blood pressure due to a renal loss of sodium. Genetically, BS is classified into 5 subtypes according to the underlying genetic defects, and BS is clinically categorized into antenatal BS and classical BS according to onset... |
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- Original Article
- Polymorphisms of the NR3C1 gene in Korean children with nephrotic syndrome
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Hee Yeon Cho, Hyun Jin Choi, So Hee Lee, Hyun Kyung Lee, Hee Kyung Kang, Il Soo Ha, Yong Choi, Hae Il Cheong
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Clin Exp Pediatr. 2009;52(11):1260-1266. Published online November 15, 2009
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Purpose : Idiopathic nephrotic syndrome (NS) can be clinically classified as steroid-sensitive and steroid-resistant. The detailed mechanism of glucocorticoid action in NS is currently unknown.
Methods : In this study, we investigated 3 known single nucleotide polymorphisms (SNPs) (ER22/23EK, N363S, and BclI) of the glucocorticoid receptor gene (the NR3C1 gene) in 190 children with NS using polymerase chain reaction-restriction fragment... |
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- Case Report
- A case of a child with non-parasitic chyluria
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Da Eun Jung, Ja Wook Koo, Sang Woo Kim, Hae Il Cheong
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Clin Exp Pediatr. 2006;49(3):326-328. Published online March 15, 2006
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Chyluria is the passage of milky urine due to the leakage of lymph into the urinary tract. Chyluria occurs predominantly in adults and is rare in children. We present an unusual case in which a child with proteinuria, hematuria and milky urine was subsequently diagnosed with non-parasitic chyluria. Retrograde cystogram confirmed a lymphatico-calyceal communication. This case showed spontaneous remission. The... |
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- Original Article
- Urinary Tract Infections in Febrile Infants under Three Months of Age
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Byung Wook Eun, Yoo Mi Chung, Hee Gyung Kang, Il Soo Ha, Hae Il Cheong, Hoan Jong Lee, Yong Choi
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Clin Exp Pediatr. 2003;46(3):265-270. Published online March 15, 2003
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Purpose : To characterize the infants under 3 months of age with urinary tract infections(UTIs), and especially patients with bacteremia or meningitis
Methods : Hospital records of all the infants under 3 months of age discharged from our hospital for 69 consecutive months with the diagnosis of initial episode of UTI were reviewed. UTI was defined when patients had fever with... |
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- Case Report
- A Case of Systemic Capillary Leak Syndrome in a Child
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Taeg Young Lee, Yoo Mi Chung, Hee Gyung Kang, Il Soo Ha, Hae Il Cheong, Yong Choi
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Clin Exp Pediatr. 2002;45(10):1292-1297. Published online October 15, 2002
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Systemic capillary leak syndrome(SCLS) is a rare disorder of unknown etiology, which is characterized
by recurrent attacks of hypotension, hemoconcentration, and hypoalbuminemia. Urinary or
enteric loss of protein is not demonstrated. It is often associated with monoclonal gammopathy,
but does not manifest multiple myeloma. Since Clarkson et al. described the first case in a 34-
year-old woman, about 50 cases have been reported in... |
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- Original Article
- Factors Associated with Renal Failure in Children with Primary Vesicoureteral Reflux
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Kyung Mi Park, Kyung Hoon Paek, Jae Hong Min, Jung Su Kim, Il Soo Ha, Kwang Myung Kim, Hae Il Cheong, Hwang Choi, Yong Choi
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Clin Exp Pediatr. 1999;42(7):959-965. Published online July 15, 1999
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Purpose : The pathophysiologic mechanisms and risk factors of renal functional deterioration are still controversial. We analyzed the factors associated with renal failure in children with primary vesicoureteral reflux.
Methods : The medical records of 166 children who were diagnosed with primary vesicoureteral reflux from Jan. 1985 to Dec. 1996 in the Department of Pediatrics, Seoul National University Children's Hospital... |
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- Renal Problems in Wilson Disease
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Il Soo Ha, Jun Ho Lee, Yeon Ho Choe, Hae Il Cheong, Sei Won Yang, Young Yull Koh, Jeong Kee Seo, Yong Choi
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Clin Exp Pediatr. 1999;42(6):817-824. Published online June 15, 1999
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Purpose : Wilson disease is a hereditary metabolic disorder characterized by an accumulation of copper in tissues which sometimes results in renal problems. This study was performed to evaluate the prevalences of the renal problems in Wilson disease and related risk factors.
Methods : In 31 patients with Wilson disease, we looked for renal problems by history taking, physical examination... |
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- Case Report
- Two Cases of Oculocerebrorenal Syndrome of Lowe
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So Won Kim, Young Suk Yu, In-One Kim, Hae Il Cheong, Yong Seung Hwang, Yong Choi
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Clin Exp Pediatr. 1999;42(3):419-423. Published online March 15, 1999
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Oculocerebrorenal syndrome of Lowe(OCRL) is a rare X-linked disorder characterized by congenital cataract(oculo-), hypotonia, developmental delay, cognitive impairment(cerebro-), renal tubular dysfunction(renal), and growth retardation. Recently, the defective gene, OCRL-1 gene encoding [PtdIns(4,5)P2] 5-phosphatase, was cloned with mutations identified in patients. Although there have been about 200 cases of OCRL reported in English literature, only three reports have been published in... |
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- Original Article
- Type I Vitamin D Dependent Rickets
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Soo Ja Hwang, Jung Soo Kim, Hae Il Cheong, Yong Choi
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Clin Exp Pediatr. 1998;41(7):877-882. Published online July 15, 1998
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Purpose : Vitamin D dependent rickets(VDDR) is a rare, autosomal recessively transmitted disorder characterized by hypocalcemia, hypophosphatemia, increased alkaline phosphatase, secondary hyperparathyroidism and many other clinical features. Type Ⅰ VDDR arises from primary deficiency in the renal 1α-hydroxylase that produces 1,25(OH)2D3. So patients with type I VDDR require life long administration of vitamin D.
Methods : There had been 6 children(4... |
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- A Case of Successful Treatment of Pulmonary Alveolar Hemorrhage with Plasmapheresis in Child with Systemic Lupus Erythematosus
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Jae Hong Min, Kyung Hoon Paek, Kyung Mi Park, Jin Soon Hwang, Jung Sue Kim, Il Soo Ha, Hae Il Cheong, Kyou Seup Han, Yong Choi
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Clin Exp Pediatr. 1998;41(7):974-978. Published online July 15, 1998
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Seoul National University College of Medicine, Seoul, Korea
Pulmonary hemorrhage is a rare but possibly fatal complication of systemic lupus erythematosus(SLE). We report a case of massive pulmonary hemorrhage in a 14-year-old boy recently diagnosed as SLE. He developed massive pulmonary hemorrhage during the courses of i.v. methylprednisolone pulse therapy, and did not respond to i.v. cyclophosphamide. However, he rapidly... |
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- Case Report
- A Case of Congenital Nephrotic Syndrome due to Diffuse Mesangial Sclerosis
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Jung-Jin Yu, Dong Kyu Jin, Hae Il Cheong, Hyun Soon Lee, Yong Choi
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Clin Exp Pediatr. 1998;41(3):415-419. Published online March 15, 1998
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Diffuse mesangial sclerosis(DMS) is one of the underlying pathology of congenital and infantile nephrotic syndrome. Infants with DMS develop nephrotic syndrome before 2 years of age and progress to end stage renal disease within 3 years of age. The authors experienced a case of isolated DMS in a 4-month-old male infant who had nephrotic syndrome for 1 month. The diagnosis... |
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- Original Article
- Longterm Follow-up of Autosomal Recessive Polycystic Kidney Disease
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June Huh, Il Soo Ha, Hae Il Cheong, Jeong Kee Seo, Yong Choi
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Clin Exp Pediatr. 1998;41(12):1693-1699. Published online December 15, 1998
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Purpose : This study was aimed to assess the clinical manifestations and courses of autosomal recessive polycystic kidney disease(ARPKD).
Methods : The medical records of 10 children diagnosed as infantile or juvenile ARPKD at Seoul National University Children's Hospital between January, 1984 and December, 1996, were reviewed, retrospectively.
Results : The average age at diagnosis was 3 8/12 years(4months-7 3/12 years)... |
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- Long-term Follow-up Study of Children with Minimal Change Nephrotic Syndrome
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Jung Sue Kim, Hae Il Cheong, Hyun Soon Lee, Yong Choi
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Clin Exp Pediatr. 1998;41(12):1675-1684. Published online December 15, 1998
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Purpose : Most of childhood MCNS has a long disease course with frequent relapses. This study was designed to analyze the long-term clinical course of childhood MCNS, focusing at relapsing pattern, treatment response and complications.
Mothods : The medical records of 137 children with biopsy-proven MCNS observed during 1976 ti 1996 were analyzed retrospectively. They were classified as initial responders(111 patients,... |
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- Case Report
- Three Cases of Cardiac Arrythmias Associated with Intravenous Methylprednisolone Pulse Therapy
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Jun Ho Lee, Jun Huh, Myung Dong Shin, Dong Kyu Jin, Il Soo Ha, Hae Il Cheong, Chung Il Noh, Yong Choi
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Clin Exp Pediatr. 1997;40(3):393-407. Published online March 15, 1997
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Methylprednisolone(MP) is administered by means of intravenous pulse therapy especially in the patients with focal segmental glomerulosclerosis(FSGS). There have been reports of its complications in a few increasing frequency. We experienced three cases of cardiaccomplications during intravenous pulsetherapy.Therewere onecaseof2¡ÆA-V block(Mobitztype I) and two cases of bradycardia and hypotension. In the former,2¡ÆA-V block in the first case deveoloped 45 hours after... |
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- Original Article
- The Prevalence of A985G Mutation in Medium Chain Acyl-Coenzyme A Dehydrogenase(MCAD) Gene in Neonates Determined from Guthrie Card
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Baeck Hee Lee, Hye Won Park, Moon Soo Park, Ho Jin Park, Yong Choi, Hae Il Cheong
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Clin Exp Pediatr. 1997;40(12):1645-1650. Published online December 15, 1997
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Purpose : Medium chain acyl-CoA dehydrogenase(MCAD) deficiency is an autosomal recessive
disoder of β oxidation of fatty acids and characterized by episodic hypoglycemia, vomiting,
convulsion, encephalopathy, apnea, and sudden death related to fasting or infection resembling Reye
syndrome or sudden infant death syndrome. In acute stage, mortality rate is very high and
survivors have significant risk of developmental disability and chronic somatic illness. However,... |
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- Primary Distal Renal Tubular Acidosis in Children
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Byoung Chul Kang, Hye Won Park, Il Soo Ha, Hae Il Cheong, Yong Choi
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Clin Exp Pediatr. 1996;39(7):987-996. Published online July 15, 1996
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Purpose : This study was designed to examine the clinical characteristics and the effect of
treatment in children with primary distal renal tubular acidosis (dRTA).
Methods : Medical records of 4 children diagnosed as dRTA at Seoul National University
Children's Hospital were reviewed, and the clinical manifestations, laboratory findings, diagnostic
criteria and effects of treatments were investigated.
Results : All cases presented with growth retardation.... |
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- Case Report
- A Case of Mauriac's syndrome
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Se Young Kim, Choong Ho Shin, Il Soo Ha, Hae Il Cheong, Sei Won Yang, Yong Choi, Hyung Ro Moon
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Clin Exp Pediatr. 1996;39(7):1020-1024. Published online July 15, 1996
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Mauriac's syndrome was described in the 1920s, as a triad of poorly controlled insulin
dependent diabetes mellitus, profound growth retardation, and hepatomgaly. Following the wide
availability of insulin and intensification of diabetic control, this entity has become quite rare. A
9-year-old female child was transferred to pediatric OPD of SNUCH because of hyperglycemia,
short stature, and visual disturbance. Five years prior to admission, she... |
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- Antiphospholipid Syndrome Presented with Pulmonary Embolism and Deep Venous Thrombosis in Child
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Ran Lee, Il Soo Ha, Hae Il Cheong, Yong Choi
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Clin Exp Pediatr. 1996;39(5):722-726. Published online May 15, 1996
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Antiphospholipid syndrome is a thrombotic disorder and the serologic marker of the
syndrome is antiphospholipid antibody(lupus anticoagulant, anticardiolpin antibody, or both). In a 13-year-old girl who presented with dyspnea, pulmonary embolism and
femoral vein thrombosis were demonstrated by lung scan and abdominal ultrasonography.
She had 3 out of 11 criteria for the diagnosis of SLE, such as thrombocytopenia, positive antinuclear antibody, low C3... |
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- Isolated Splenic Infarction in a Girl with Systemic Lupus Erythematosus
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Kyung Ran Park, Hee Eun Lee, Yun Ae Jeon, Il Soo Ha, Hae Il Cheong, Joong Gon Kim, Yong Choi
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Clin Exp Pediatr. 1996;39(4):562-566. Published online April 15, 1996
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Splenic infarction is a rare disease and usually detected as a complication of SBE, atrial fibrillation, hemoglobinopathy, or myeloproliperative disorders. Although thrombotic event, such as deep vein, cerebral or renal thrombosis, is a frequent complication of SLE, there have been only a couple of cases documenting splenic infarction complicated in SLE. This is, to our knowledge, the first case report... |
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- Original Article
- Clinicopathological Study about Childhood Primary Nephrotic Syndrome Resistant to 4-week Daily Steroid Therapy
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Jung Sue Kim, Il Soo Ha, Hae Il Cheong, Yong Choi
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Clin Exp Pediatr. 1996;39(12):1729-1735. Published online December 15, 1996
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Purpose : Steroid-resistant nephrotic syndrome in children is difficult to manage and tends to
progress to chronic renal failure. We studied clinicopathological correlations in primary nephrotic
syndrome in children resistant to 4-week daily steroid therapy.
Methods : Among children who had been admitted to Seoul National University Children's
Hospital during the period between Oct. 1985 and Jul. 1995 and diagnosed as primary nephrotic
syndrome, 87... |
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- Case Report
- A Pediatric Case of MELAS Syndrome Associated with Insulin-dependent Diabetes Mellitus
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Kyung Ran Park, Hye Won Park, Tae Sung Ko, Hae Il Cheong, Sei Won Yang, Young Seung Hwang, In Won Kim, Je Geun Chi
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Clin Exp Pediatr. 1996;39(10):1461-1465. Published online October 15, 1996
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MELAS(mitochondrial myopathy, encephalopathy, lactic acidosis, and sroke like episodes) is a
major subgroup of heterogeneous mitochondrial encephalopathy. Recent advances in molecular
genetics revealed specific mutations in the mitochondrial DNA causing MELAS. We described
clinical and molecular genetic findings of a 13-year-old boy with MELAS syndrome associated
IDDM(insulin dependent diabetes mellitus). For molecular genetic studies, DNAs from peripheral
blood nucleated cells were used. And the A→G... |
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- Original Article
- Acute Hemorrhagic Cystitis(AHC) in Children -Etiology and Clinical Characteristics-
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Jin Won Pyo, Eun Hwa Choi, Jin Young Park, Hoan Jong Lee, Hae Il Cheong, Il Soo Ha, Yong Choi, Kwang Myung Kim, Hwang Choi, Je Geun Chi
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Clin Exp Pediatr. 1995;38(2):207-215. Published online February 15, 1995
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Purpose : AHC characterized by sudden onset of gross hematuria, dysuria and frequency oc curs in children and young adults as a self-limited disease that should be differentiated from se rious renal disorders. We have performed this study to establish the cause and characterize the clinical features of this illness in Korean children.
Methods : 19 cases collected prospectively for 30... |
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- Case Report
- Recurrent Hematuria due to Renal Hypouricemia
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Kyu Young Kim, Il Soo Ha, Hae Il Cheong, Yong Choi
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Clin Exp Pediatr. 1995;38(1):129-132. Published online January 15, 1995
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A marked low concentration of serum uric acid(0.7-1.2mg/dl) was detected in a 14-year-old boy with recurrent episodes of gross hematuria. The hypouricemia accompanied with a markedly increased urinary clearance of uric acid (32.6-56.0ml/min), which was only minimally changed after both the administration of pyrazinamide, and inhibitor of the renal tubular secretion of uric acid, and the administration of probenecid, and... |
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- Original Article
- Pheochromocytoma in Children
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Tae Sue Ha, Jae Hong Park, Il Soo Ha, Hae Il Cheong, Yong Choi, Hyung Ro Moon, Gui Won Park
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Clin Exp Pediatr. 1994;37(7):961-968. Published online July 15, 1994
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We Reviewed 10 hypertensive children with pheochromocytoma retrospectively and the following results were obtained.
1) Out of 10 patients, 7 were male and 3 female. Age ranged from 5.5 years to 13.8 years and their median age was 9.9 years.
2) They complained of sweating, lethargy, headache, or chest pain and so on, Hypertension were noticed in all patients. Heart murmurs were... |
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- A Clinical Observation on Lupus Nephritis in Children
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Kang Mo Ahn, Jae Sung Ko, Hye Won Park, Il Soo Ha, Hae Il Cheong, Yong Choi, Hee Joo Kim
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Clin Exp Pediatr. 1994;37(6):842-849. Published online June 15, 1994
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We reviewed the clinical features, histrologic patterns and clinical courses of 30 children with lupus nephritis retrospectively, and the results were summerized as follows;
1) The male to female ratio was 1:2.8, and the mean age at the onset was 108/12 years.
2) The clinical symptoms were diverse, and malaise, weight loss, anorexia, fever and malar rash were the most frequent findings.
3)... |
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- Hypophosphatemic Rickets
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Jae un, June Huh, Il Soo Ha, Hae Il Cheong, Yong Choi
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Clin Exp Pediatr. 1994;37(3):376-382. Published online March 15, 1994
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The clinical data of 27 patients with hypophosphatemic rickets treated with phosphate and 1 α-hydroxyvitamin D were analysed retrospectively. The median age at diagnosis was 4 years, and the main clinical manifestations were bowleg and short stature. Among total 24 families, 5 families(21%) had X-linked dominant mode of inheritance, 1 family (4%) had autosomal dominant mode and 17 families (71%)... |
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- Serum Alkaline Phosphatase Activity after Intravenous Administration of Albumin Preparation
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June Huh, Kang Mo Ahn, Ja Wook Koo, Il Soo Ha, Hae Il Cheong, Yong Choi
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Clin Exp Pediatr. 1993;36(6):830-836. Published online June 15, 1993
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Serum alkaline phosphatase(AP) activity is elevated in hepatobiliary disease, bone disease, pregnancy and certain neoplasms. Recently we experienced marked elevation of serum AP activity after administration of ablumin preparation in nephrotic patients who suffered from hypovolemic symptoms. So serum AP activity and the isoenzymes in the albumin preparations & patient뭩 serum after the administration of albumin preparation were studied. Serum... |
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- Nephrotic Syndrome under 2 Years of Age
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Jae Sung Ko, Kang Mo Ahn, Hye Won Park, Il Soo Ha, Hae Il Cheong, Yong Choi, Kwang Wook Ko
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Clin Exp Pediatr. 1993;36(10):1395-1401. Published online October 15, 1993
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There had been total 20 patients with early onset (4 months~2 years) primary nephrotic syndrome in the Deparment of Pediatrics, Seoul National University Children's Hospital, during the period from March 1987 to February 1993. We analysed clinical courses, response to treatment, pathological findings and prognosis of the patients And the results were as follows;
1) The initial responders to steroid treatment... |
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- Original Article
- Acute Renal Failure Following Cardiac Surgery
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Kang Yong Park, Yeon Ho Choi, Tae Sun Ha, Il Soo Ha, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Joon Ryang Rho
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Clin Exp Pediatr. 1992;35(9):1198-1209. Published online September 15, 1992
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A retrospective study of 452 patients who undertook cardiac surgery was performed to determine the pevalence, etiology, and clinical features of postoperative acute renal failure(ARF). The overall incidence of ARF following cardiac surgery was 4.65%(21/452). The incidence of ARF following open heart surgery(OHS) was 5.11%, and that following closed heart surgery was 2.50%. Preoperactive risk factors noted in the development... |
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- Acquired Renal Cystic Disease in Childhood Chronic Renal Failure
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Tae Sun Ha, Seong Hoon Ha, Il Soo Ha, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Woo Sun Kim, Kim In One
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Clin Exp Pediatr. 1992;35(8):1044-1050. Published online August 15, 1992
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The authors evaluated 19 childrenwith chronic renal failure patients diagnosed and followed up at the Department of Pediatrics, Seoul National University Hospital for the detection of acquired renal cystic disease (ARCD) with two radiologists by the means of ultrasonography.
The results were as follows:
1) Of the 19 patients, male to femals ratio was 14:5 and of them, hemodialysis and peritoneal dialysis... |
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- A Clinical Aspect of the Hemolytic Uremic Syndrome
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Hye Won Park, Tae Sun Ha, Il Soo Ha, Hae Il Cheong, Yong Choi, Kwang Wook Ko
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Clin Exp Pediatr. 1992;35(7):909-920. Published online July 15, 1992
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We reviewed the medical records of 14 children (8 girls, 6 boys), diagnosed as hemolytic uremic syndrome at Seoul National University Children뭩 Hospital from 1981 to 1990. The age at presentation ranged from 1 month to 10 years, with a mean age of 2.7 years. Only eight (57.1%) of the children had diarrheal prodrome and five (35.7%) had grossly bloody... |
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- Acute renal failure with back pain after exercise.
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Hae Jung Park, Mi Jung Kim, Dong Kyu Jin, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Jung Mi Park, Kyung Mo Yeun
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Clin Exp Pediatr. 1991;34(6):863-868. Published online June 30, 1991
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We have experienced one case of acute renal failure without clinical rhabdomyolysis characterized
by preceding exercise and back pain. This patient showed patch renal increased uptakes in bone scan
with 99mTechnetium-methylene diphosphonate, and delayed wedge-shaped contrast enhancements in
renal computed tomography. These findings can be explained by focal renal vasoconstriction of
interlobar arteries or arcuate arteries, which may be considered as one of the... |
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- A clinical study of continuous ambulatory peritoneal dialysis in childhood.
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Tae Sun Ha, Hye Won Park, Ja Wook Koo, In Seok Lim, Hae Il Cheong, Yong Choi, Kwang Wook Ko
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Clin Exp Pediatr. 1991;34(3):363-370. Published online March 31, 1991
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A retrospective analysis of clinical with findings in 24 children continuous ambulatory peritoneal
dialysis (CAPD) who were admitted to the Department of Pediatrics, Seoul National University
Children’s Hospital from March, 1987 till August, 1990 was performed and the results were as follows;
1) The male to female ratio was 16:8, and the age distribution at the beginning of CAPD was from
59 days to 16.5... |
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- IgA Nephropathy in Childhood.
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Yong Choi, Dong Woo Son, Ja Wook Koo, Dong Kyu Jin, Hae Il Cheong, Kwang Wook Ko, Hyun Soon Lee, Yong Il Kim
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Clin Exp Pediatr. 1990;33(9):1237-1243. Published online September 30, 1990
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In this study we compared between the patients with recurrent gross hematuria (group 1, n=45) and
* with nephrotic range proteinuria (group 2, n=21) in IgA nephropathy who were admitted to Seoul
National University Children’s Hospital during the period from January, 1980 to December, 1989.
The results of the study were as follows.
1) Age of onset and sex ratio were not different between the... |
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- A Clinical Study on the Posterior Subcapsular Cataracts in Childhood Nephrotic Syndrome.
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Dong Kyu Jin, Ja Wook Koo, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Jong Hoon Lee, Young Suk Yu
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Clin Exp Pediatr. 1990;33(8):1097-1103. Published online August 31, 1990
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A clinical study was carried out in 73 children with nephrotic syndrome who had had regular
ophthalmologic examination annually at Seoul National University Children’s Hospital from March
1976 to February 1990 with the aim of finding the relationship between the posterior subcapsular
cataract (PSC) and the effect of corticosteroids. The results were summarized as follows:
1) The number of patients with PSC were 23 cases... |
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- Recombinant Human Erythropoietin Therapy in Anemia Accompanied by Chronic Renal Failure.
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Dong Kyu Jin, Hae Il Cheong, Yong Choi, Kwang Wook Ko
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Clin Exp Pediatr. 1990;33(7):970-976. Published online July 31, 1990
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A clinical study was carried out to evaluate the efficacies of rHuEPO (recombinant human
erythropoietin) in anemia of 7 chronic renal failure patients under dialysis at Seoul National
University Children's Hospital from Feb. 1989 to Nov. 1989.
The results were as follows;
- 1) There was progressive increase of hematocrit levels in all 6 hemodialysis patients and mainte-
nance dosage of rHuEPO to sustain hemoglobin... |
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- A Case of Acute Renal Failure Associated with Rhabdomyolysis in Carbon Monoxide Intoxication.
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Kyung Hee Park, Sei Hee Hwang, Hae Il Cheong, Yong Choi, Kwang Wook Ko
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Clin Exp Pediatr. 1990;33(5):690-694. Published online May 31, 1990
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We experienced a case of acute renal failure associated with rhabdomyolysis after Carbon
Monoxide intoxication in a 12 year old Korean girl who had marked soft tissue swelling of the left
thigh, reddish brown colored urine and oliguria.
Diagnosis was made by clinical features, markedly elevated serum muscle enzymes and serum
myoglobin, and Tc 99m-MDP bone scan which revealed increased radioactivity at the left... |
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- Juvenile Nephronophyjisis in An Infant.
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Young Seo Park, Chang Youn Lee, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Je Geun Chi, Chang Bin Im
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Clin Exp Pediatr. 1989;32(8):1155-1160. Published online August 31, 1989
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Juvenile nephronophthisis is a chronic tubulo-interstitial renal disease characterized by an early
onset of polyuria and polydipsia, decreased urinary concentrating ability, anemia, growth retardation
and progressive renal disease. It is recognized as an important cause of chronic renal failure in the
childhood. However only one case was reported in the Korean literatures.
In this paper we have reported the second documented case of juvenile... |
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- Urinary Tract Anomalies in Congenital Heart Disease.
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Chang Youn Lee, Young Seo Park, Hae Il Cheong, Jung Yun Choi, Young Soo Yun, Yong Choi, Kwang Wook Ko, In One Kim, Kyung Mo Yeun, Kwang Myung Kim, Hwang Choi
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Clin Exp Pediatr. 1989;32(6):804-808. Published online June 30, 1989
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A variety of urinary tract anomalies were detected in 1,569 children with congenital heart disease
during their cardiac evaluation with cardiac cineangiography in the Department of Pediatrics, Seoul
National University Children’s Hospital within a period from October 1985 to April 1988.
The incidence, nature and course of these urinary tract anomalies were analyzed and the results
were as follows;
1) The number of male children... |
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- A Case of Renovascular Hypertension.
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Kang Oh Lee, Soo Gi Kang, Mi Ja Yoon, Hyung Ja Park, Bok Lyun Kim, Shin na Kim, Hae Il Cheong, In One Kim, Kyung Mo Yeon
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Clin Exp Pediatr. 1989;32(5):705-712. Published online May 31, 1989
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Recently, we experienced a case of renovascular hypertension in 7 year-old boy, who came with
chief complaints of protracted vomiting and severe headache for 2 days. Right after admission, he
developed seizure and loss of consciousness lasting 5 minutes. Blood pressure was 230/180 mmHg at
that time. Diagnostic studies were done with plasma renin activity, rapid sequence pyelography and
arteriography, which showed severe focal... |
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- Hypercalciuria in Children with Hematuria.
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Tae Sung Ko, Chang Youn Lee, Young Seo Park, Hae Il Cheong, Yong Choi, Kwang Wook Ko
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Clin Exp Pediatr. 1989;32(5):644-652. Published online May 31, 1989
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Ten children with gross hematuria were diagnosed as hypercalciuria in the Department of
Pediatrics, Seoul National University Children’s Hospital during the period from June 1983 to Aug.
1987. We reviewed their clinical data, retrospectively, and could obtain the following results.
1) The age at the onset of gross hematuria ranged from 4 months to 10 7/12 years, and the male
to female ratio was... |
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- Continuous Arteriovenous Hemofiltration in Children.
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Hae Il Cheong, Dong Kyu Jin, Young Seo park, Yong Choi, Kwang Wook Ko
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Clin Exp Pediatr. 1989;32(2):230-238. Published online February 28, 1989
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Among those who were admitted to the Pediatric Intensive Care Unit (PICU), Seoul National
University Children’s Hospital and developed acute renal failure (ARF) during the disease course, 11
children received continuous arteriovenous hemofiltration (CAVH) by pediatricians during a 3-year-
period from Nov. 85 to Oct. 88. Their clinical findings were analyzed retrospectively, and the results
were as follows;
1) They were 5 boys and 6... |
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- Plasma Renin Activity (PRA) in Peripheral Vein and Renal Veins in Normotensive Children with Cyanotic Congenital Heart Disease.
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Sang Kyu Park, Hae Il Cheong, Chung Il Noh, Yong Soo Yun, Yong Choi, Kwang Wook Ko
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Clin Exp Pediatr. 1988;31(8):1021-1027. Published online August 31, 1988
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PRA’s in peripheral vein, both renal veins, and inferior vena cava (IVC) were measured in 25
normotensive children without renal disease undergoing cardiac catheterization for their underlying
cyanotic congenital heart disease. And we presented the results as reference values/ranges of PRA in
children.
1) There was no significant difference in PRA between both side renal veins at any absolute PRA
levels with a mean ratio (RT/LT)... |
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- Clinical Observation on Hemodialysis in Children with Chronic Renal Failure.
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Hae Il Cheong, Yong Choi, Kwang Wook Ko
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Clin Exp Pediatr. 1988;31(5):590-596. Published online May 31, 1988
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There had been total 21 children with end stage renal disease in whom hemodialysis was done in
the pediatric dialysis unit of Seoul National University Children’s Hospital during the period from
1986. 3. 31 to 1987. 11. 30. And we took a retrospective review of their clinical data, and the results
were as follows
1) Primary glomerular disease, H enoch-Schdnlein nephritis, and reflux nephropathy were... |
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- A Study on Minimal Change Nephrotic Syndrome in Children.
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Yong Choi, Hong Jin Lee, Hae Il Cheong, Kwang Wook Ko, Hyun Soon Lee, Yong Il Kim
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Clin Exp Pediatr. 1988;31(2):220-226. Published online February 28, 1988
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To assess the clinical significance of histopathologic variants of minimal change nephrotic syn-
drome (MCNS) by light microscopic findings, 148 biopsy proven MCNS patients, who were admitted
to Seoul National University Hospital between the period from January 1976 to December 1986, were
analyzed according to clinical findings, steroid responsiveness, and follow up status in relation to the
pathologic variants.
The followings are summary and conclusion.
1) Significantly... |
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- Urinary Red Blood Cell Morphology in Hematuria.
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Hong Jin Lee, Chang Yeon Lee, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Myung Hee Park
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Clin Exp Pediatr. 1988;31(11):1460-1467. Published online November 30, 1988
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We have studied morphological alterations in urinary RBC as a tool for the differential diagnosis
of hematuria in children, that is, differentiation of glomerular bleeding from nonglomerular bleeding,
and the results were as follows;
1) Urinary RBCs from glomerular diseases showed higher rate of dysmorphism (84.3±16.8%), and
those from nonglomerular diseases did lower one (15.2 ±12.9%) with phase contrast microscopic
examination.
2) Simple light microscopic examination after Wright’s... |
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- A Clinical Observation on Systemic Lupus Erythematosus in Children.
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Han Wook Yoo, Hae Il Cheong, Hoan Jong Lee, Yong Choi, Kwang Wook Ko, Yong Il Kim
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Clin Exp Pediatr. 1987;30(5):527-535. Published online May 31, 1987
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To elucidate the clinical characteristics of childhood onset systemic lupus erythematosus (SLE), we
carried out a retrospective review on medical records of sixteen patients who were diagnosed as SLE
on the base of “the 1982 revised criteria for the SLE” (by American Rheumatism Association) at the
Department of Pediatrics, Seoul National University Children’s Hospital between January 1976 and July 1986.
The results were summarized... |
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- Idiopathic IgA Nepropathy in Children.
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Hae Il Cheong, Han Wook Yoo, Kwang Wook Ko
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Clin Exp Pediatr. 1986;29(6):633-643. Published online June 30, 1986
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We analyzed clinical findings, pathological findings and clinico-pathological correlations in 55 children with idiopathic IgA nephropathy confirmed immunopathologically, and the results were as follows;
1) The mean age at onset was 9.65±2.45 years with relatively even distribution in school ages and males
outnumbered females by 1.75 : 1.
2) The main mode of presentation was typical... |
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- Primary Peritonitis in Children with Nephrotic Syndrome.
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Hae Il Cheong, Whan Jong Lee, Jeong Kee Seo, Yong Choi, Kwang Wook Ko
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Clin Exp Pediatr. 1985;28(7):695-704. Published online July 31, 1985
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Thirty episodes of primary peritonitis in 22 children with nephrotic syndrome who had admitted in the Department of Pediatrics, Seoul National University Hospital from Jan. *81 to Sept. ’84 were studied, and the results were as follows; 1)Among 22 children, male to female ratio was 16 : 6 and the mean age at the onset of
peritonitis was 7.80 years (average... |
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- Plasma Renin Activity (PRA) in Peripheral Vein and Renal Veins in Normotensive Children.
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Chong Ku Yun, Hae Il Cheong, Chung Il Noh, Jung Yun Choi, Yong Choi, Kwang Wook Ko, Kyung Mo Yeon
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Clin Exp Pediatr. 1985;28(6):555-563. Published online June 30, 1985
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PRA in peripheral vein, both renal veins and both inferior vena cava (JVC) both proximal and distal to the drainage of the both renal veins was measured in 80 normotensive children with no renal disease undergoing routine cardiac catheterization due to congenital heart disease which did not cause significant hemodynamic changes in most of them. And we presented the results... |
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- Heart Disease Screening for Primary School Children.
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Chang Yee Hong, In Sil Lee, Hee Ju Kim, Jung Hwan Choi, Hae Il Cheong, Jung Yun Choi, Yong Soo Yun
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Clin Exp Pediatr. 1985;28(3):258-262. Published online March 31, 1985
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A heart disease screening program was performed on 15,685 primary school children in Seoul City from the first to sixth grade to estimate the prevalence of heart diseases. Among the 15,685 children examined, 45 were confirmed to have heart disease (2.9/1,000) Out of the 45 children, 38 had congenital heart disease(2.4/1,000) and 7 had rheumatic heart disease(0.4/1,000) and the ratio... |
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- Idiopathic Membranoproliferative Glomerulonephritis in Children.
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Hae Il Cheong, Hee Shang Youn, Whan Jong Lee, Yong Choi, Kwang Wook Ko, Yong Il Kim
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Clin Exp Pediatr. 1985;28(1):45-57. Published online January 31, 1985
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Among total 452 children with percutaneous kidney needle biopsy due to renal disease in the Department of Pediatric, Seoul National University Hospital, from Jan. 75 to Nov.84, 20(4.4%) were confirmed as
embranoproliferative glomerulonephritis(MPGN) histopathologically. And 4 out of these 20 were excluded from this report because of association of systemic disease. A review of clinical and pathological findings of the... |
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- Case Report
- Rifampin Induced Nonresponsiveness to Steroid Therapy in Children with Minimal Change Nephrotic Syndrome .
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Hae Il Cheong, Sang Bok Suk, Yong Choi, Kwang Wook Ko
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Clin Exp Pediatr. 1984;27(5):506-510. Published online May 31, 1984
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We experienced three children with the biopsy proven minimal change nephrotic syndrome who had failed to respond to prednisolone, 60 mg/m2/d for 4 to 9 weeks due to concomittent administration of rifampin.
Because rifampin is a known enzyme inducer of the liver like phenobarbital and dilantin which can increase the clearance of the other drugs such as steroid etc., rifampin were... |
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- Original Article
- Renal Disease in Children-A Ten-Years Experience.
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Hee Young Shin, Hae Il Cheong, Yong Choi, Kwang Wook Ko
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Clin Exp Pediatr. 1983;26(7):681-686. Published online July 31, 1983
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Statistical analysis of inpatients of Seoul National University Hospital from 1972 to 1981
who had renal diseases was performed with respect to their disease pattern, annual incidence
of each disease, and age distribution.
From 1972 to 1981 renal disease was found in 831 patients among 11,226 total inpatients
(7.4%). Male to female ratio of renal disease patients was 2.2 to 1, while male to... |
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- Clinical Observation of Juvenile Diabetes Millitus.
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Hae Il Cheong, Dong Gyoon Kim, Yong Choi, Kwang Wook Ko
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Clin Exp Pediatr. 1983;26(6):553-563. Published online June 30, 1983
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Clinical data of 33 children with juvenile diabetes mellitus who were admitted to the Seoul
National University Hospital from Jan. 1967 to Feb. 1983 were analyzed retrospectively.
Male to female ratio was 10:23, the mean age at onset was 6 10/12 years, and there was
considerable seasonal variation with peaks in late winter and spring.
Polyuria and polydipsia were noted in all cases as... |
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- Lipoprotein Profiles in Minimal Change Nephrotic Syndrome.
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Yong Choi, Heui Jeen Kim, Hae Il Cheong, Jeong Kee Seo, Kwang Wook Ko
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Clin Exp Pediatr. 1983;26(3):237-246. Published online March 31, 1983
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Data obtained from 59 hospitalized patients with minimal change nephrotic syndrome which
was confirmed by kidney biopsy, were analyzed for serum albumin, serum lipids, 24hr urine
protein, creatinine clearanee, HDL-eholesterol. In 38 of the patients, lipoproteins were analyzed.
The following results were obained
1. Serum phospolipid (PL) was increased whenever serum total cholesterol (TC) was
increased but to a lesser degree. The ratio of TC/PL were... |
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- Clinical Studies on Total Anomalous Pulmonary Venous Connection.
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Young Jin Hong, Kee Hong Kwon, Hae Il Cheong, Jung Yeun Choi, Yong Soo Yoon, Chang Yee Hong
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Clin Exp Pediatr. 1982;25(11):1120-1130. Published online November 30, 1982
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Total anomalous pulmonary venous connection (TAPVC) is a rare congenital defect in which
all the pulmonary veins are connected to the right atrium or its tributary veins. Without
surgical intervention, most patients with TAP VC have grave prognosis, with cardiac failure
and death in infancy. But owing to the advances of surgical technique and postoperative care,
complete correction has been accomplished with good results.
Sixteen... |
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- Long Term Follow-up Study of Chidren with nephrotic Syndron (over 5years).
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Hae Il Cheong, Whan Chong Lee, Yong Choi, Cwang wook Ko
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Clin Exp Pediatr. 1980;23(2):130-142. Published online February 15, 1980
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Follow-up study of fifty two children with nephrome who had once admitted to the pediatric ward of S.N.U.H were presented with regards to response to initial steroid therapy, relapsing patterns, and factors affecting prognosis. All patients were followed up for more than 5 years and the mean period of follow-up was 7 7/12 years, and in two patients, follow-up for... |
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- Case Report
- A Case of Chylous Ascites in an Infant Boy.
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Kyu Chan Kim, Hae Il Cheong, Yong Choi, Hyung Ro Moon
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Clin Exp Pediatr. 1980;23(1):63-67. Published online January 15, 1980
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The authors report a case of chylous ascites in a two month old boy with massive ascites. He was managed with repeated therapeutic paracentesis and skimmed milk feeding. A marked improvement was resulted in clinical symptoms and laboratory findings at the time of discharge to be followed-up at the outpatient service. A brief review of literatures is included |
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